The Effect of pineaple juice (Ananas comosus) on Blood Cholesterol Level of Rabbit (Oryctolagus cuniculus) hipercholesterolemia

Zuhrawati N. A.


This study aims to know the effect of pineapple juice on blood cholesterol level of male hypercholesterolemic rabbits. A total of 12 local
male rabbits aged 1-2 years with body weight ranging from 0.9-1.6 kg were used as sampel. Sample were divided randomly into 4 treatment
groups, each group consisting of 3 replications. All rabbits were initially examined for the total cholesterol levels, before fed with a diet to make
hypercholesterolemic. The rabbits were then fed with a mixture of 90% sugar solution as much as 6 gr/kg body weight and egg yolks as much as
3 gr/kg body weight for 7 consecutive days using a stomach sonde, followed with re-examination of total cholesterol. Samples were then
administered with pineapple juice on KI (10 g /kg BW), KII (20 g/kg BW), and KIII (30 g/kg), while the K0 as controls were not given pineapple
juice. After 10 days of administration of pineapple juice, rabbit blood was collected through the auricular vein for total cholesterol examination
using the Chod-PAP. Data were analyzed by ANOVA completely randomized design (CRD) one way, and the difference between the treatment
group was examined using Duncan's multiple test. Results showed that the mean (±SD) of total blood cholesterol levels of rabbits (mg/dl) groups
K0, KI, KII, and KIII after the administration of pineapple juice in a row was 176.60 ± 57.10; 66.60±12.50; 63±17.70; and 57.60±24.80.
Statistical analysis showed that treatment affect significantly (P<0.05) to decrease total blood cholesterol levels of rabbits. In conclusion, the
administration of pineapple juice (Ananas comosus) for ten consecutive days can decrease blood total cholesterol of hypercholesterolemia
Key words: diet cholesterol, pineapple juice, total cholesterol levels, rabbit

Full Text:





  • There are currently no refbacks.

Copyright (c) 2016 by author and J. Med. Vet.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Creative Commons License
J. Med. Vet. is licensed under a Creative Commons Attribution 4.0 International License.